Thyroxine Differentially Modulates the Peripheral Clock: Lessons from the Human Hair Follicle

The human hair follicle (HF) exhibits peripheral clock activity, with knock-down of clock genes (BMAL1 and PER1) prolonging active hair growth (anagen) and increasing pigmentation. Similarly, thyroid hormones prolong anagen and stimulate pigmentation in cultured human HFs. In addition they are recog...

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Detalles Bibliográficos
Autores principales: Hardman, Jonathan A., Haslam, Iain S., Farjo, Nilofer, Farjo, Bessam, Paus, Ralf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4379003/
https://www.ncbi.nlm.nih.gov/pubmed/25822259
http://dx.doi.org/10.1371/journal.pone.0121878

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4379003/
https://www.ncbi.nlm.nih.gov/pubmed/25822259
http://dx.doi.org/10.1371/journal.pone.0121878

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