Lesion of the Olfactory Epithelium Accelerates Prion Neuroinvasion and Disease Onset when Prion Replication Is Restricted to Neurons

Natural prion diseases of ruminants are moderately contagious and while the gastrointestinal tract is the primary site of prion agent entry, other mucosae may be entry sites in a subset of infections. In the current study we examined prion neuroinvasion and disease induction following disruption of...

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Detalles Bibliográficos
Autores principales: Crowell, Jenna, Wiley, James A., Bessen, Richard A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4379011/
https://www.ncbi.nlm.nih.gov/pubmed/25822718
http://dx.doi.org/10.1371/journal.pone.0119863

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4379011/
https://www.ncbi.nlm.nih.gov/pubmed/25822718
http://dx.doi.org/10.1371/journal.pone.0119863

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