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Vinpocetine Reduces Carrageenan-Induced Inflammatory Hyperalgesia in Mice by Inhibiting Oxidative Stress, Cytokine Production and NF-κB Activation in the Paw and Spinal Cord

Vinpocetine is a safe nootropic agent used for neurological and cerebrovascular diseases. The anti-inflammatory activity of vinpocetine has been shown in cell based assays and animal models, leading to suggestions as to its utility in analgesia. However, the mechanisms regarding its efficacy in infl...

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Detalles Bibliográficos
Autores principales: Ruiz-Miyazawa, Kenji W., Zarpelon, Ana C., Pinho-Ribeiro, Felipe A., Pavão-de-Souza, Gabriela F., Casagrande, Rubia, Verri, Waldiceu A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4379066/
https://www.ncbi.nlm.nih.gov/pubmed/25822523
http://dx.doi.org/10.1371/journal.pone.0118942