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A polymorphism in HLA-G modifies statin benefit in asthma

Several reports have shown that statin treatment benefits patients with asthma, however inconsistent effects have been observed. The mir-152 family (148a, 148b and 152) has been implicated in asthma. These microRNAs suppress HLA-G expression, and rs1063320, a common SNP in the HLA-G 3’UTR which is a...

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Detalles Bibliográficos
Autores principales: Naidoo, Devesh, Wu, Ann C, Brilliant, Murray H, Denny, Joshua, Ingram, Christie, Kitchner, Terrie E, Linneman, James G, McGeachie, Michael J, Roden, Dan M, Shaffer, Christian M, Shah, Anushi, Weeke, Peter, Weiss, Scott T, Xu, Hua, Medina, Marisa W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4379135/
https://www.ncbi.nlm.nih.gov/pubmed/25266681
http://dx.doi.org/10.1038/tpj.2014.55