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Bradykinin Release Avoids High Molecular Weight Kininogen Endocytosis

Human H-kininogen (120 kDa) plays a role in many pathophysiological processes and interacts with the cell surface through protein receptors and proteoglycans, which mediate H-kininogen endocytosis. In the present work we demonstrate that H-kininogen containing bradykinin domain is internalized and d...

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Detalles Bibliográficos
Autores principales: Damasceno, Igor Z., Melo, Katia R. B., Nascimento, Fabio D., Souza, Daianne S. P., Araujo, Mariana S., Souza, Sinval E. G., Sampaio, Misako U., Nader, Helena B., Tersariol, Ivarne L. S., Motta, Guacyara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4379145/
https://www.ncbi.nlm.nih.gov/pubmed/25822177
http://dx.doi.org/10.1371/journal.pone.0121721