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Bradykinin Release Avoids High Molecular Weight Kininogen Endocytosis
Human H-kininogen (120 kDa) plays a role in many pathophysiological processes and interacts with the cell surface through protein receptors and proteoglycans, which mediate H-kininogen endocytosis. In the present work we demonstrate that H-kininogen containing bradykinin domain is internalized and d...
Autores principales: | Damasceno, Igor Z., Melo, Katia R. B., Nascimento, Fabio D., Souza, Daianne S. P., Araujo, Mariana S., Souza, Sinval E. G., Sampaio, Misako U., Nader, Helena B., Tersariol, Ivarne L. S., Motta, Guacyara |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4379145/ https://www.ncbi.nlm.nih.gov/pubmed/25822177 http://dx.doi.org/10.1371/journal.pone.0121721 |
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