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Development of an In Vitro Assay and Demonstration of Plasmodium berghei Liver-Stage Inhibition by TRAP-Specific CD8(+) T Cells

The development of an efficacious vaccine against the Plasmodium parasite remains a top priority. Previous research has demonstrated the ability of a prime-boost virally vectored sub-unit vaccination regimen, delivering the liver-stage expressed malaria antigen TRAP, to produce high levels of antige...

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Detalles Bibliográficos
Autores principales: Longley, Rhea J., Bauza, Karolis, Ewer, Katie J., Hill, Adrian V. S., Spencer, Alexandra J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4379172/
https://www.ncbi.nlm.nih.gov/pubmed/25822951
http://dx.doi.org/10.1371/journal.pone.0119880