The Dynamic Conformational Cycle of the Group I Chaperonin C-Termini Revealed via Molecular Dynamics Simulation

Chaperonins are large ring shaped oligomers that facilitate protein folding by encapsulation within a central cavity. All chaperonins possess flexible C-termini which protrude from the equatorial domain of each subunit into the central cavity. Biochemical evidence suggests that the termini play an i...

Descripción completa

Detalles Bibliográficos
Autores principales: Dalton, Kevin M., Frydman, Judith, Pande, Vijay S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4379175/
https://www.ncbi.nlm.nih.gov/pubmed/25822285
http://dx.doi.org/10.1371/journal.pone.0117724

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4379175/
https://www.ncbi.nlm.nih.gov/pubmed/25822285
http://dx.doi.org/10.1371/journal.pone.0117724

Ejemplares similares