Pooled Sequencing and Rare Variant Association Tests for Identifying the Determinants of Emerging Drug Resistance in Malaria Parasites

We explored the potential of pooled sequencing to swiftly and economically identify selective sweeps due to emerging artemisinin (ART) resistance in a South-East Asian malaria parasite population. ART resistance is defined by slow parasite clearance from the blood of ART-treated patients and mutatio...

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Detalles Bibliográficos
Autores principales: Cheeseman, Ian H., McDew-White, Marina, Phyo, Aung Pyae, Sriprawat, Kanlaya, Nosten, François, Anderson, Timothy J.C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Methods
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4379400/
https://www.ncbi.nlm.nih.gov/pubmed/25534029
http://dx.doi.org/10.1093/molbev/msu397

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4379400/
https://www.ncbi.nlm.nih.gov/pubmed/25534029
http://dx.doi.org/10.1093/molbev/msu397

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