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Observing in real time the evolution of artemisinin resistance in Plasmodium falciparum

Simple genetic changes that correlate with drug resistance are used routinely to identify resistant pathogens. These “molecular markers” have usually been defined long after the phenotype of resistance was noted. The molecular changes at the “end game” reflect a long and complex evolution of genetic...

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Detalles Bibliográficos
Autor principal: Sibley, Carol Hopkins
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4379603/
https://www.ncbi.nlm.nih.gov/pubmed/25889405
http://dx.doi.org/10.1186/s12916-015-0316-5