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Observing in real time the evolution of artemisinin resistance in Plasmodium falciparum
Simple genetic changes that correlate with drug resistance are used routinely to identify resistant pathogens. These “molecular markers” have usually been defined long after the phenotype of resistance was noted. The molecular changes at the “end game” reflect a long and complex evolution of genetic...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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BioMed Central
2015
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4379603/ https://www.ncbi.nlm.nih.gov/pubmed/25889405 http://dx.doi.org/10.1186/s12916-015-0316-5 |