The multivesicular body is the major internal site of prion conversion

The conversion of the properly folded prion protein, PrPc, to its misfolded amyloid form, PrPsc, occurs as the two proteins traffic along the endocytic pathway and PrPc is exposed to PrPsc. To determine the specific site of prion conversion, we knocked down various proteins in the endocytic pathway...

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Detalles Bibliográficos
Autores principales: Yim, Yang-In, Park, Bum-Chan, Yadavalli, Rajgopal, Zhao, Xiaohong, Eisenberg, Evan, Greene, Lois E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4379730/
https://www.ncbi.nlm.nih.gov/pubmed/25663703
http://dx.doi.org/10.1242/jcs.165472

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4379730/
https://www.ncbi.nlm.nih.gov/pubmed/25663703
http://dx.doi.org/10.1242/jcs.165472

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