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(5R)-5-Hydroxytriptolide (LLDT-8) inhibits osteoclastogenesis via RANKL/RANK/OPG signaling pathway

BACKGROUND: The aim of this study was to investigate the regulative activity of (5R)-5-hydroxytriptolide (LLDT-8) on receptor activator of nuclear factor κ-B ligand (RANKL)/receptor activator of nuclear factor κ-B (RANK)/Osteoprotegerin (OPG) system in rheumatoid arthritis (RA) and its anti-osteocla...

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Detalles Bibliográficos
Autores principales: Shen, Yi, Jiang, Ting, Wang, Rongsheng, He, Shijun, Guo, Mengru, Zuo, Jianping, He, Dongyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4379732/
https://www.ncbi.nlm.nih.gov/pubmed/25887296
http://dx.doi.org/10.1186/s12906-015-0566-y