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Hypoxia down-regulates expression of secretory leukocyte protease inhibitor in bronchial epithelial cells via TGF-β1

BACKGROUND: Secretory leukocyte protease inhibitor (SLPI) is a protein with anti-protease and antimicrobial properties that is constitutively secreted from the airway epithelium. The importance of maintaining a balance between proteases and anti-proteases, and robust innate defence mechanisms in the...

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Detalles Bibliográficos
Autores principales: Påhlman, Lisa I, Jögi, Annika, Gram, Magnus, Mori, Michiko, Egesten, Arne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4379733/
https://www.ncbi.nlm.nih.gov/pubmed/25851169
http://dx.doi.org/10.1186/s12890-015-0016-0