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Hypoxia down-regulates expression of secretory leukocyte protease inhibitor in bronchial epithelial cells via TGF-β1
BACKGROUND: Secretory leukocyte protease inhibitor (SLPI) is a protein with anti-protease and antimicrobial properties that is constitutively secreted from the airway epithelium. The importance of maintaining a balance between proteases and anti-proteases, and robust innate defence mechanisms in the...
Autores principales: | Påhlman, Lisa I, Jögi, Annika, Gram, Magnus, Mori, Michiko, Egesten, Arne |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4379733/ https://www.ncbi.nlm.nih.gov/pubmed/25851169 http://dx.doi.org/10.1186/s12890-015-0016-0 |
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