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Changes in the regulation of the Notch signaling pathway are temporally correlated with regenerative failure in the mouse cochlea

Sensorineural hearing loss is most commonly caused by the death of hair cells in the organ of Corti, and once lost, mammalian hair cells do not regenerate. In contrast, other vertebrates such as birds can regenerate hair cells by stimulating division and differentiation of neighboring supporting cel...

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Detalles Bibliográficos
Autores principales: Maass, Juan C., Gu, Rende, Basch, Martin L., Waldhaus, Joerg, Lopez, Eduardo Martin, Xia, Anping, Oghalai, John S., Heller, Stefan, Groves, Andrew K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4379755/
https://www.ncbi.nlm.nih.gov/pubmed/25873862
http://dx.doi.org/10.3389/fncel.2015.00110