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Premature aging of leukocyte DNA methylation is associated with type 2 diabetes prevalence

BACKGROUND: Type 2 diabetes mellitus (T2D) is highly prevalent in Middle-Eastern and North African Arab populations, but the molecular basis for this susceptibility is unknown. Altered DNA methylation levels were reported in insulin-secreting and responding tissues, but whether methylation in access...

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Detalles Bibliográficos
Autores principales: Toperoff, Gidon, Kark, Jeremy D, Aran, Dvir, Nassar, Hisham, Ahmad, Wiessam Abu, Sinnreich, Ronit, Azaiza, Dima, Glaser, Benjamin, Hellman, Asaf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4379765/
https://www.ncbi.nlm.nih.gov/pubmed/25829970
http://dx.doi.org/10.1186/s13148-015-0069-1