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Accumulation of amyloid-like Aβ(1–42) in AEL (autophagy–endosomal–lysosomal) vesicles: potential implications for plaque biogenesis
Abnormal accumulation of Aβ (amyloid β) within AEL (autophagy–endosomal–lysosomal) vesicles is a prominent neuropathological feature of AD (Alzheimer's disease), but the mechanism of accumulation within vesicles is not clear. We express secretory forms of human Aβ(1–40) or Aβ(1–42) in Drosophil...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Society for Neurochemistry
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4379859/ https://www.ncbi.nlm.nih.gov/pubmed/24521233 http://dx.doi.org/10.1042/AN20130044 |