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Large-scale production and protein engineering of G protein-coupled receptors for structural studies

Structural studies of G protein-coupled receptors (GPCRs) gave insights into molecular mechanisms of their action and contributed significantly to molecular pharmacology. This is primarily due to technical advances in protein engineering, production and crystallization of these important receptor ta...

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Detalles Bibliográficos
Autores principales: Milić, Dalibor, Veprintsev, Dmitry B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4379943/
https://www.ncbi.nlm.nih.gov/pubmed/25873898
http://dx.doi.org/10.3389/fphar.2015.00066