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Highly sensitive targeted methylome sequencing by post-bisulfite adaptor tagging
The current gold standard method for methylome analysis is whole-genome bisulfite sequencing (WGBS), but its cost is substantial, especially for the purpose of multi-sample comparison of large methylomes. Shotgun bisulfite sequencing of target-enriched DNA, or targeted methylome sequencing (TMS), ca...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4379973/ https://www.ncbi.nlm.nih.gov/pubmed/25324297 http://dx.doi.org/10.1093/dnares/dsu034 |