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MUSCLE: automated multi-objective evolutionary optimization of targeted LC-MS/MS analysis

Summary: Developing liquid chromatography tandem mass spectrometry (LC-MS/MS) analyses of (bio)chemicals is both time consuming and challenging, largely because of the large number of LC and MS instrument parameters that need to be optimized. This bottleneck significantly impedes our ability to esta...

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Detalles Bibliográficos
Autores principales: Bradbury, James, Genta-Jouve, Grégory, Allwood, J. William, Dunn, Warwick B., Goodacre, Royston, Knowles, Joshua D., He, Shan, Viant, Mark R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4380028/
https://www.ncbi.nlm.nih.gov/pubmed/25388146
http://dx.doi.org/10.1093/bioinformatics/btu740