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M(3)D: a kernel-based test for spatially correlated changes in methylation profiles

Motivation: DNA methylation is an intensely studied epigenetic mark implicated in many biological processes of direct clinical relevance. Although sequencing-based technologies are increasingly allowing high-resolution measurements of DNA methylation, statistical modelling of such data is still chal...

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Detalles Bibliográficos
Autores principales: Mayo, Tom R., Schweikert, Gabriele, Sanguinetti, Guido
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4380032/
https://www.ncbi.nlm.nih.gov/pubmed/25398611
http://dx.doi.org/10.1093/bioinformatics/btu749