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Evaluation of chemical phototoxicity, focusing on phosphorylated histone H2AX

Histone H2AX is a minor component of nuclear histone H2A. The phosphorylation of histone H2AX at Ser 139, termed γ-H2AX, was originally identified as an early event after the direct formation of DNA double-strand breaks (DSBs) by ionizing radiation. Now, the generation of γ-H2AX is also considered t...

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Detalles Bibliográficos
Autores principales: Ibuki, Yuko, Toyooka, Tatsushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4380052/
https://www.ncbi.nlm.nih.gov/pubmed/25480829
http://dx.doi.org/10.1093/jrr/rru105