Neuroprotective effects of activated protein C on intrauterine inflammation-induced neonatal white matter injury are associated with the downregulation of fibrinogen-like protein 2/fibroleukin prothrombinase and the inhibition of pro-inflammatory cytokine expression

Maternal intrauterine inflammation or infection is an important risk factor for neonatal cerebral white matter injury (WMI) and future neurological deficits. Activated protein C (APC), a natural anticoagulant, has been shown to exhibit anti-inflammatory, anti-apoptotic, profibrinolytic and cytoprote...

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Detalles Bibliográficos
Autores principales: JIN, SHENG-JUAN, LIU, YAN, DENG, SHI-HUA, LIAO, LI-HONG, LIN, TU-LIAN, NING, QIN, LUO, XIAO-PING
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2015
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4380123/
https://www.ncbi.nlm.nih.gov/pubmed/25777531
http://dx.doi.org/10.3892/ijmm.2015.2136

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4380123/
https://www.ncbi.nlm.nih.gov/pubmed/25777531
http://dx.doi.org/10.3892/ijmm.2015.2136

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