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Notch1-Dll4 signaling and mechanical force regulate leader cell formation during collective cell migration
At the onset of collective cell migration, a subset of cells within an initially homogenous population acquires a distinct “leader” phenotype with characteristic morphology and motility. However, the factors driving leader cell formation as well as the mechanisms regulating leader cell density durin...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4380165/ https://www.ncbi.nlm.nih.gov/pubmed/25766473 http://dx.doi.org/10.1038/ncomms7556 |