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Spirotetronate Polyketides as Leads in Drug Discovery

[Image: see text] The discovery of chlorothricin (1) defined a new family of microbial metabolites with potent antitumor antibiotic properties collectively referred to as spirotetronate polyketides. These microbial metabolites are structurally distinguished by the presence of a spirotetronate motif...

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Detalles Bibliográficos
Autores principales:	Lacoske, Michelle H., Theodorakis, Emmanuel A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society and American Society of Pharmacognosy 2014
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4380204/ https://www.ncbi.nlm.nih.gov/pubmed/25434976 http://dx.doi.org/10.1021/np500757w

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