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Myosin-binding protein C corrects an intrinsic inhomogeneity in cardiac excitation-contraction coupling
The beating heart exhibits remarkable contractile fidelity over a lifetime, which reflects the tight coupling of electrical, chemical, and mechanical elements within the sarcomere, the elementary contractile unit. On a beat-to-beat basis, calcium is released from the ends of the sarcomere and must d...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4380226/ https://www.ncbi.nlm.nih.gov/pubmed/25839057 http://dx.doi.org/10.1126/sciadv.1400205 |