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Myosin-binding protein C corrects an intrinsic inhomogeneity in cardiac excitation-contraction coupling

The beating heart exhibits remarkable contractile fidelity over a lifetime, which reflects the tight coupling of electrical, chemical, and mechanical elements within the sarcomere, the elementary contractile unit. On a beat-to-beat basis, calcium is released from the ends of the sarcomere and must d...

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Detalles Bibliográficos
Autores principales: Previs, Michael J., Prosser, Benjamin L., Mun, Ji Young, Previs, Samantha Beck, Gulick, James, Lee, Kyounghwan, Robbins, Jeffrey, Craig, Roger, Lederer, W. J., Warshaw, David M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4380226/
https://www.ncbi.nlm.nih.gov/pubmed/25839057
http://dx.doi.org/10.1126/sciadv.1400205