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TDP-43 as a possible biomarker for frontotemporal lobar degeneration: a systematic review of existing antibodies

Frontotemporal lobar degeneration (FTLD) is one of the leading causes of dementia after Alzheimer’s disease. A high-ranking candidate to become a diagnostic marker for a major pathological subtype of FTLD is the transactive response DNA binding protein of 43 kDa (TDP-43). The main objective is to el...

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Detalles Bibliográficos
Autores principales: Goossens, Joery, Vanmechelen, Eugeen, Trojanowski, John Q, Lee, Virginia MY, Van Broeckhoven, Christine, van der Zee, Julie, Engelborghs, Sebastiaan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4380254/
https://www.ncbi.nlm.nih.gov/pubmed/25853864
http://dx.doi.org/10.1186/s40478-015-0195-1