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Induction of tumor initiation is dependent on CD44s in c-Met(+) hepatocellular carcinoma
BACKGROUND: Hepatocellular carcinoma (HCC) patients with active hepatocyte growth factor (HGF)/c-Met signaling have a significantly worse prognosis. c-Met, a high affinity receptor for HGF, plays a critical role in cancer growth, invasion and metastasis. c-Met and CD44 have been utilized as cell sur...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4380258/ https://www.ncbi.nlm.nih.gov/pubmed/25886575 http://dx.doi.org/10.1186/s12885-015-1166-4 |