Induction of tumor initiation is dependent on CD44s in c-Met(+) hepatocellular carcinoma

BACKGROUND: Hepatocellular carcinoma (HCC) patients with active hepatocyte growth factor (HGF)/c-Met signaling have a significantly worse prognosis. c-Met, a high affinity receptor for HGF, plays a critical role in cancer growth, invasion and metastasis. c-Met and CD44 have been utilized as cell sur...

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Detalles Bibliográficos
Autores principales: Dang, Hien, Steinway, Steven N, Ding, Wei, Rountree, Carl B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4380258/
https://www.ncbi.nlm.nih.gov/pubmed/25886575
http://dx.doi.org/10.1186/s12885-015-1166-4

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