Breaking the Hydrophobicity of the MscL Pore: Insights into a Charge-Induced Gating Mechanism

The mechanosensitive channel of large conductance (MscL) is a protein that responds to membrane tension by opening a transient pore during osmotic downshock. Due to its large pore size and functional reconstitution into lipid membranes, MscL has been proposed as a promising artificial nanovalve suit...

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Detalles Bibliográficos
Autores principales: Chandramouli, Balasubramanian, Di Maio, Danilo, Mancini, Giordano, Barone, Vincenzo, Brancato, Giuseppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4380313/
https://www.ncbi.nlm.nih.gov/pubmed/25825909
http://dx.doi.org/10.1371/journal.pone.0120196

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4380313/
https://www.ncbi.nlm.nih.gov/pubmed/25825909
http://dx.doi.org/10.1371/journal.pone.0120196

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