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Selective and Genetic Constraints on Pneumococcal Serotype Switching

Streptococcus pneumoniae isolates typically express one of over 90 immunologically distinguishable polysaccharide capsules (serotypes), which can be classified into “serogroups” based on cross-reactivity with certain antibodies. Pneumococci can alter their serotype through recombinations affecting t...

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Detalles Bibliográficos
Autores principales: Croucher, Nicholas J., Kagedan, Lisa, Thompson, Claudette M., Parkhill, Julian, Bentley, Stephen D., Finkelstein, Jonathan A., Lipsitch, Marc, Hanage, William P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4380333/
https://www.ncbi.nlm.nih.gov/pubmed/25826208
http://dx.doi.org/10.1371/journal.pgen.1005095