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Selective and Genetic Constraints on Pneumococcal Serotype Switching
Streptococcus pneumoniae isolates typically express one of over 90 immunologically distinguishable polysaccharide capsules (serotypes), which can be classified into “serogroups” based on cross-reactivity with certain antibodies. Pneumococci can alter their serotype through recombinations affecting t...
Autores principales: | Croucher, Nicholas J., Kagedan, Lisa, Thompson, Claudette M., Parkhill, Julian, Bentley, Stephen D., Finkelstein, Jonathan A., Lipsitch, Marc, Hanage, William P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4380333/ https://www.ncbi.nlm.nih.gov/pubmed/25826208 http://dx.doi.org/10.1371/journal.pgen.1005095 |
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