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Identification and Therapeutic Potential of a Vitronectin Binding Region of Meningococcal Msf

The human pathogen Neisseria meningitides (Nm) attains serum resistance via a number of mechanisms, one of which involves binding to the host complement regulator protein vitronectin. We have shown previously that the Meningococcal surface fibril (Msf), a trimeric autotransporter, binds to the activ...

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Detalles Bibliográficos
Autores principales: Hill, Darryl J., Griffiths, Natalie J., Borodina, Elena, Andreae, Clio A., Sessions, Richard B., Virji, Mumtaz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4380367/
https://www.ncbi.nlm.nih.gov/pubmed/25826209
http://dx.doi.org/10.1371/journal.pone.0124133