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Identification and Therapeutic Potential of a Vitronectin Binding Region of Meningococcal Msf
The human pathogen Neisseria meningitides (Nm) attains serum resistance via a number of mechanisms, one of which involves binding to the host complement regulator protein vitronectin. We have shown previously that the Meningococcal surface fibril (Msf), a trimeric autotransporter, binds to the activ...
Autores principales: | Hill, Darryl J., Griffiths, Natalie J., Borodina, Elena, Andreae, Clio A., Sessions, Richard B., Virji, Mumtaz |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4380367/ https://www.ncbi.nlm.nih.gov/pubmed/25826209 http://dx.doi.org/10.1371/journal.pone.0124133 |
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