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Retinoic Acid Can Exacerbate T Cell Intrinsic TLR2 Activation to Promote Tolerance

The contribution of vitamin A to immune health has been well established. However, recent evidence indicates that its active metabolite, retinoic acid (RA), has the ability to promote both tolerogenic and inflammatory responses. While the outcome of RA-mediated immunity is dependent upon the immunol...

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Detalles Bibliográficos
Autores principales: Nguyen, Vivien, Pearson, Kandyce, Kim, Jee-Hyun, Kamdar, Karishma, DePaolo, R. William
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4380421/
https://www.ncbi.nlm.nih.gov/pubmed/25826367
http://dx.doi.org/10.1371/journal.pone.0118875