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Large-Scale Chemical Similarity Networks for Target Profiling of Compounds Identified in Cell-Based Chemical Screens

Target identification is one of the most critical steps following cell-based phenotypic chemical screens aimed at identifying compounds with potential uses in cell biology and for developing novel disease therapies. Current in silico target identification methods, including chemical similarity datab...

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Detalles Bibliográficos
Autores principales: Lo, Yu-Chen, Senese, Silvia, Li, Chien-Ming, Hu, Qiyang, Huang, Yong, Damoiseaux, Robert, Torres, Jorge Z.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4380459/
https://www.ncbi.nlm.nih.gov/pubmed/25826798
http://dx.doi.org/10.1371/journal.pcbi.1004153