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Large-Scale Chemical Similarity Networks for Target Profiling of Compounds Identified in Cell-Based Chemical Screens
Target identification is one of the most critical steps following cell-based phenotypic chemical screens aimed at identifying compounds with potential uses in cell biology and for developing novel disease therapies. Current in silico target identification methods, including chemical similarity datab...
Autores principales: | Lo, Yu-Chen, Senese, Silvia, Li, Chien-Ming, Hu, Qiyang, Huang, Yong, Damoiseaux, Robert, Torres, Jorge Z. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4380459/ https://www.ncbi.nlm.nih.gov/pubmed/25826798 http://dx.doi.org/10.1371/journal.pcbi.1004153 |
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