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AMPK modulates Hippo pathway activity to regulate energy homeostasis

The Hippo pathway was discovered as a conserved tumour suppressor pathway restricting cell proliferation and apoptosis. However, the upstream signals that regulate the Hippo pathway in the context of organ size control and cancer prevention are largely unknown. Here, we report that glucose, the ubiq...

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Detalles Bibliográficos
Autores principales: Wang, Wenqi, Xiao, Zhen-Dong, Li, Xu, Aziz, Kathryn E., Gan, Boyi, Johnson, Randy L., Chen, Junjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4380807/
https://www.ncbi.nlm.nih.gov/pubmed/25751139
http://dx.doi.org/10.1038/ncb3113