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Analyses of Allele-Specific Gene Expression in Highly Divergent Mouse Crosses Identifies Pervasive Allelic Imbalance

Complex human traits are influenced by variation in regulatory DNA through mechanisms that are not fully understood. Since regulatory elements are conserved between humans and mice, a thorough annotation of cis regulatory variants in mice could aid in this process. Here we provide a detailed portrai...

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Detalles Bibliográficos
Autores principales: Crowley, James J, Zhabotynsky, Vasyl, Sun, Wei, Huang, Shunping, Pakatci, Isa Kemal, Kim, Yunjung, Wang, Jeremy R, Morgan, Andrew P, Calaway, John D, Aylor, David L, Yun, Zaining, Bell, Timothy A, Buus, Ryan J, Calaway, Mark E, Didion, John P, Gooch, Terry J, Hansen, Stephanie D, Robinson, Nashiya N, Shaw, Ginger D, Spence, Jason S, Quackenbush, Corey R, Barrick, Cordelia J, Nonneman, Randal J., Kim, Kyungsu, Xenakis, James, Xie, Yuying, Valdar, William, Lenarcic, Alan B, Wang, Wei, Welsh, Catherine E, Fu, Chen-Ping, Zhang, Zhaojun, Holt, James, Guo, Zhishan, Threadgill, David W, Tarantino, Lisa M, Miller, Darla R, Zou, Fei, McMillan, Leonard, Sullivan, Patrick F, de Villena, Fernando Pardo-Manuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4380817/
https://www.ncbi.nlm.nih.gov/pubmed/25730764
http://dx.doi.org/10.1038/ng.3222