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Understanding genetic variation in in vivo tolerance to artesunate: implications for treatment efficacy and resistance monitoring

Artemisinin-based drugs are the front-line weapon in the treatment of human malaria cases, but there is concern that recent reports of slow clearing infections may signal developing resistance to treatment. In the absence of molecular markers for resistance, current efforts to monitor drug efficacy...

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Detalles Bibliográficos
Autores principales: Pollitt, Laura C, Sim, Derek, Salathé, Rahel, Read, Andrew F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4380923/
https://www.ncbi.nlm.nih.gov/pubmed/25861387
http://dx.doi.org/10.1111/eva.12194