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Cell shape and the microenvironment regulate nuclear translocation of NF-κB in breast epithelial and tumor cells

Although a great deal is known about the signaling events that promote nuclear translocation of NF-κB, how cellular biophysics and the microenvironment might regulate the dynamics of this pathway is poorly understood. In this study, we used high-content image analysis and Bayesian network modeling t...

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Detalles Bibliográficos
Autores principales: Sero, Julia E, Sailem, Heba Zuhair, Ardy, Rico Chandra, Almuttaqi, Hannah, Zhang, Tongli, Bakal, Chris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4380925/
https://www.ncbi.nlm.nih.gov/pubmed/26148352
http://dx.doi.org/10.15252/msb.20145644