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Open pipelines for integrated tumor genome profiles reveal differences between pancreatic cancer tumors and cell lines

We describe open, reproducible pipelines that create an integrated genomic profile of a cancer and use the profile to find mutations associated with disease and potentially useful drugs. These pipelines analyze high-throughput cancer exome and transcriptome sequence data together with public databas...

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Detalles Bibliográficos
Autores principales: Goecks, Jeremy, El-Rayes, Bassel F, Maithel, Shishir K, Khoury, H Jean, Taylor, James, Rossi, Michael R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4380965/
https://www.ncbi.nlm.nih.gov/pubmed/25594743
http://dx.doi.org/10.1002/cam4.360