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iRNA-seq: computational method for genome-wide assessment of acute transcriptional regulation from total RNA-seq data

RNA-seq is a sensitive and accurate technique to compare steady-state levels of RNA between different cellular states. However, as it does not provide an account of transcriptional activity per se, other technologies are needed to more precisely determine acute transcriptional responses. Here, we ha...

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Detalles Bibliográficos
Autores principales: Madsen, Jesper Grud Skat, Schmidt, Søren Fisker, Larsen, Bjørk Ditlev, Loft, Anne, Nielsen, Ronni, Mandrup, Susanne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4381047/
https://www.ncbi.nlm.nih.gov/pubmed/25564527
http://dx.doi.org/10.1093/nar/gku1365