CarD stabilizes mycobacterial open complexes via a two-tiered kinetic mechanism

CarD is an essential and global transcriptional regulator in mycobacteria. While its biological role is unclear, CarD functions by interacting directly with RNA polymerase (RNAP) holoenzyme promoter complexes. Here, using a fluorescent reporter of open complex, we quantitate RP(o) formation in real...

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Detalles Bibliográficos
Autores principales: Rammohan, Jayan, Ruiz Manzano, Ana, Garner, Ashley L., Stallings, Christina L., Galburt, Eric A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Nucleic Acid Enzymes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4381055/
https://www.ncbi.nlm.nih.gov/pubmed/25697505
http://dx.doi.org/10.1093/nar/gkv078

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4381055/
https://www.ncbi.nlm.nih.gov/pubmed/25697505
http://dx.doi.org/10.1093/nar/gkv078

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