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New insights into stop codon recognition by eRF1

In eukaryotes, translation termination is performed by eRF1, which recognizes stop codons via its N-terminal domain. Many previous studies based on point mutagenesis, cross-linking experiments or eRF1 chimeras have investigated the mechanism by which the stop signal is decoded by eRF1. Conserved mot...

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Detalles Bibliográficos
Autores principales: Blanchet, Sandra, Rowe, Michelle, Von der Haar, Tobias, Fabret, Céline, Demais, Stéphane, Howard, Mark J., Namy, Olivier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4381064/
https://www.ncbi.nlm.nih.gov/pubmed/25735746
http://dx.doi.org/10.1093/nar/gkv154