Cargando…
An LRP16-containing preassembly complex contributes to NF-κB activation induced by DNA double-strand breaks
The activation of NF-κB has emerged as an important mechanism for the modulation of the response to DNA double-strand breaks (DSBs). The concomitant SUMOylation and phosphorylation of IKKγ by PIASy and ATM, respectively, is a key event in this mechanism. However, the mechanism through which mammalia...
Autores principales: | , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4381070/ https://www.ncbi.nlm.nih.gov/pubmed/25735744 http://dx.doi.org/10.1093/nar/gkv161 |