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Hypoxia-induced gene expression results from selective mRNA partitioning to the endoplasmic reticulum
Protein synthesis is a primary energy-consuming process in the cell. Therefore, under hypoxic conditions, rapid inhibition of global mRNA translation represents a major protective strategy to maintain energy metabolism. How some mRNAs, especially those that encode crucial survival factors, continue...
Autores principales: | , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4381074/ https://www.ncbi.nlm.nih.gov/pubmed/25753659 http://dx.doi.org/10.1093/nar/gkv167 |