Hypoxia-induced gene expression results from selective mRNA partitioning to the endoplasmic reticulum

Protein synthesis is a primary energy-consuming process in the cell. Therefore, under hypoxic conditions, rapid inhibition of global mRNA translation represents a major protective strategy to maintain energy metabolism. How some mRNAs, especially those that encode crucial survival factors, continue...

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Detalles Bibliográficos
Autores principales: Staudacher, Jonas J., Naarmann-de Vries, Isabel S., Ujvari, Stefanie J., Klinger, Bertram, Kasim, Mumtaz, Benko, Edgar, Ostareck-Lederer, Antje, Ostareck, Dirk H., Bondke Persson, Anja, Lorenzen, Stephan, Meier, Jochen C., Blüthgen, Nils, Persson, Pontus B., Henrion-Caude, Alexandra, Mrowka, Ralf, Fähling, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4381074/
https://www.ncbi.nlm.nih.gov/pubmed/25753659
http://dx.doi.org/10.1093/nar/gkv167

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