An intrinsically disordered region of methyl-CpG binding domain protein 2 (MBD2) recruits the histone deacetylase core of the NuRD complex

The MBD2-NuRD (Nucleosome Remodeling and Deacetylase) complex is an epigenetic reader of DNA methylation that regulates genes involved in normal development and neoplastic diseases. To delineate the architecture and functional interactions of the MBD2-NuRD complex, we previously solved the structure...

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Detalles Bibliográficos
Autores principales: Desai, Megha A., Webb, Heather D., Sinanan, Leander M., Scarsdale, J. Neel, Walavalkar, Ninad M., Ginder, Gordon D., Williams, David C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4381075/
https://www.ncbi.nlm.nih.gov/pubmed/25753662
http://dx.doi.org/10.1093/nar/gkv168

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4381075/
https://www.ncbi.nlm.nih.gov/pubmed/25753662
http://dx.doi.org/10.1093/nar/gkv168

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