Insulin-response epigenetic activation of Egr-1 and JunB genes at the nuclear periphery by A-type lamin-associated pY19-Caveolin-2 in the inner nuclear membrane

Insulin controls transcription to sustain its physiologic effects for the organism to adapt to environmental changes added to genetic predisposition. Nevertheless, insulin-induced transcriptional regulation by epigenetic factors and in defined nuclear territory remains elusive. Here we show that inn...

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Detalles Bibliográficos
Autores principales: Jeong, Kyuho, Kwon, Hayeong, Lee, Jaewoong, Jang, Donghwan, Pak, Yunbae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4381080/
https://www.ncbi.nlm.nih.gov/pubmed/25753664
http://dx.doi.org/10.1093/nar/gkv181

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4381080/
https://www.ncbi.nlm.nih.gov/pubmed/25753664
http://dx.doi.org/10.1093/nar/gkv181

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